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Biguanide-derived neuroprotective agent (metformin) To mitigate neuroinflammation and mitochondrial dysfunction in PD, metformin was encapsulated into PLGA, which were further coated with BV2 microglial cell membranes to enhance the targeting efficiency to neuroinflammatory sites (BV2-metformin-loaded PLGA) for intranasal administration 19

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Deepika has denied the skin lightening accusations by saying "There was a rumor that I got surgery to lighten my skin, C'mon who even does that?" Kajol Before Before Now Kajol has denied the skin lightening accusations by saying that she only looked darker/tanner when she was younger because of spending too much time outside in the sun without sunscreen for work

1998 Jul;83(7):2355-60