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Mundi MS, Velapati S, Patel J, Kellogg TA, Abu Dayyeh BK, Hurt RT (2020) Evolution of NAFLD and its management

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105 A combination supplement containing the salt of berberine and ursodeoxycholic acid (Actigall) (a bile acid used to treat liver and gallbladder ailments), at a dosage of 1,000 mg twice daily, was found to reduce liver fat content, liver enzyme levels, and body weight, and improve blood glucose control more than placebo after 18 weeks in a trial that included 100 subjects with type 2 diabetes, overweight or obesity, and NAFLD, with a high likelihood of NASH