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Since these C-capsids (125 nm) are too large to pass through nuclear pores, they reach the cytoplasm by an unconventional route 30 that first involves their budding through the inner nuclear membrane, which produces enveloped perinuclear virions

Glutathione S-transferase isozymes in rat lens

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On the other hand, preclinical studies and clinical trials highlight the potent anti-inflammatory effects of TB-500 in various models of organ and tissue injury, including in the skin, eye cornea, liver, and central nervous system [34, 35, 38, 39]