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Here, we defined a novel NRF2 target gene set linked to NRF2-dependency in cancer cell lines, and observed that a significant portion of these genes is devoid of promoter-proximal NRF2 occupancy

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The astute reader may have noticed that a lot of these past studies were conducted using GLP1R agonists with much shorter half-lives (GLP1 = 5 minutes, Exenatide = 2 hours, Liraglutide = 13 hours)

It can also lead to dehydration and blood sugar fluctuations which may result in muscle spasms and may affect nerves throughout the body