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The outer membrane protein TbpA and the surface lipoprotein TbpB work together to extract iron from human transferrin, with TbpA forming the channel for iron transport across the membrane and TbpB acting as an initial binding partner that enhances iron release and transferrin removal

Depending on the virus-host interaction, virus-induced ROS production can either enhance or inhibit the replication of viruses 45,152,153,154

Currently, 8 GPxs (GPx1GPx8) have been identified in mammalian tissues, which exhibit the genetic, structural and dynamic differences and perform common and separate functions [12] (Fig