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(1989) Dec;34(6):385-7

Fallacy 3: MTHFR Means You Cant Process Folic Acid One of the most widespread misconceptions is that carrying an MTHFR C677T or TT polymorphism means you cannot process folic acid

An entirely new research program: characterization of the blends stability and pharmacokinetics, controlled animal studies of the combination with appropriate endpoints, factorial experiments to test for genuine synergy, and eventually adequately powered, randomized, placebo-controlled human trials with predefined outcomes and safety monitoring conducted under regulatory oversight

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