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Sniffer-patch recordings For sniffer patch recordings, 13 M resistance fire-polished borosilicate glass electrodes with tips coated with refined beeswax were used and filled with internal pipette solution containing (in mM): CsCl (125), Tris-creatine-PO 4 (5.4), EGTA (10.0), HEPES (5.0), CaCl 2 (2.0), MgCl 2 (1.0), pH 7.4, 281 mOsm kg 1

As LOH segments that did not delete non-synonymous variants tended to be smaller (Supplementary Fig

However, it is considered that the use of glutathione supplements may cause allergic reactions with symptoms such as cramping, swelling or rash.