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Therefore, model-informed precision dosing targeting cumulative cAUC is essential for optimizing dosing regimens

Last Published 02.01.2026 Effective Date: 02.01.2026 This policy addresses breast imaging, including digital mammography, magnetic resonance imaging (MRI), ultrasound, automated breast ultrasound system, computer-aided detection (CAD), computer-aided tactile breast imaging, electrical impedance scanning (EIS), magnetic resonance elastography (MRE), and molecular breast imaging

Non-inhaled nicotine still raises heart rate and blood pressure and is not free of vascular effect, and its addiction potential is the main reason for caution

The FLOW trial was a major step in this area