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A randomized controlled trial published in NPJ Aging and Mechanisms of Disease found that NAD+ precursor treatment increased cellular NAD+ levels by 60% and improved physical performance measures by 25% in healthy older adults (Elhassan et al., 2019)

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Patients with proliferative retinopathy should be referred for treatment according to standards of care established by pivotal studies such as the Diabetic Retinopathy Study, the ETDRS, and the Diabetic Retinopathy Clinical Research Network (DRCR) Protocol S ( Figure 1 )