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Two studies in particular deserve close examination because they represent the best available evidence for making clinical decisions

Risk factors for NAION include age (being over the age of 50), diabetes, hypertension, high cholesterol, sleep apnea, and anatomical predispositions such as a small cup-to-disc ratio

[Last accessed on 2022 Feb 27];Poster presented at:81st Scientific Sessions of the American Diabetes Association, June 25 -29, 2021 [Google Scholar] 28.Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, et al

Clinical trials show an average weight loss of 15-20% of body weight over 72 weeks, with many patients seeing noticeable results within the first few months