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The enzyme is composed of two symmetrically related subunits, shown here in cartoon backbone representation to highlight the secondary structure

Introduction Cardiovascular disease (CVD) is the main cause of morbidity and mortality in patients with type 2 diabetes (T2DM), with a relevant impact on the economic costs for health care systems and on the quality of life for many patients ( Among the novel therapies, great interest has been aroused by sodiumglucose cotransporter-2 inhibitors (SGLT2-i) and glucagon-like peptide-1 receptor agonist (GLP1-RA), that have changed the management of diabetic patients

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This should be individualized based on age, kidney function, and other health factors in consultation with your healthcare provider