indication for semaglutide Two-year effects of in adults with overweight or obesity: the STEP 5 trial Comparative safety and side effects

Slow gastric emptying: It delays the rate at which the stomach empties its contents, leading to a more gradual absorption of glucose, which is beneficial for managing blood sugar levels in type 2 diabetes mellitus

Clinical guidelines from endocrinology societies recommend baseline cardiovascular assessment, kidney function testing, and family history evaluation before GLP-1 use

Fatigue and general discomfort, which tend to resolve with time

To qualify for weight-management treatment, patients typically need a BMI of 27 or higher, with most programs also considering weight-related health conditions such as high blood pressure, type 2 diabetes, or high cholesterol