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99,100 Activation of AMPK stimulates glucose uptake in muscles and beta oxidation, in which fatty acids are broken down, while reducing the production of fat and cholesterol in the liver

What Is Tirzepatide and How Does It Work Tirzepatide is a once-weekly injectable medication that works by activating two hormone receptors simultaneously: the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

Biochemistry 32, 1328813298