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The HPA axis, your body stress response system, plays an equally critical role

Overall, both classes are indifferently recommended by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) as first-line therapy in patients with T2DM and established ASCVD or multiple ASCVD risk factors to reduce the risk of major adverse cardiovascular events (MACE), such as myocardial infarction, stroke, and cardiovascular death [6, 7]

Without peer-reviewed, head-to-head comparative studies, everything else is just educated guesswork

Statements Author contributions FB-B and MM-R: drafting original manuscript