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They also stimulate insulin secretion in pancreatic -cells, but their effects on glucagon production in pancreatic -cells differ, with GIP having a glucagonotropic effect during hypoglycemia and GLP-1 exhibiting glucagonostatic effect during hyperglycemia

(R)-3-amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one derivatives as potent inhibitors of dipeptidyl peptidase-4: design, synthesis, biological evaluation, and molecular modeling

[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Kripp A.M., Feichter A., Knig D

Semaglutide to syntetyczny, dugo dziaajcy agonista receptora GLP-1