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Such studies could also help further our understanding of the pathophysiological basis of the change in GLP-1 levels seen in this study

Figure 5 4.4 Direct TAM cancer cell ferroptosis interactions: a mechanistic narrative Tumor-associated macrophages (TAMs) orchestrate ferroptotic sensitivity in cancer cells through a set of tightly interlinked metabolic and immunological interactions ( Bidirectional signaling further reinforces this crosstalk: tumor-cellderived lactate, HMGB1, prostaglandins, and oxidized lipids polarize macrophages toward either ferroptosis-promoting (M1-like) or ferroptosis-restraining (M2-like) states

As a result, previous studies have examined the eryptotic properties of bisphenol A (BPA) and its substitute bisphenol S (BPS) [422], brominated flame retardants (BFRs) [421], and organophosphate flame retardants (OPFRs) [428]