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It mimics the effects of a hormone called GLP-1, which the body naturally releases after a person eats food

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After 8 weeks of TAC, -MSH-treated mice showed attenuated LV hypertrophy compared to vehicle-treated TAC mice as evidenced by reduction in ventricular weight, ventricular weight-to-tibia length ratio (Fig

However, their signaling diverges at later stages: in the tongue, activation of these receptors produces neurotransmission and conscious taste perception, whereas in the intestine, the same receptor types modulate hormone secretion (such as GLP-1 and GIP) through endocrine signaling pathways (48, 49)