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J Neurochem 2014, 128: 459471

In everyday practice, many patients stop or stay on lower doses (cost, side effects, access), which reduces effectiveness

A very good example is linagliptin, which is predominantly excreted through the bile rather than through the kidneys

We found that blocking the translation of NRF2 prevented GSH accumulation ( Figure 7F ) as well as negated the immunosuppressive action of melatonin treatment ( Figures 7H, I )