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Pharmacol Res 46:499503 Bae EH, Lee KS, Lee J, Ma SK, Kim NH, Choi KC, Frokiaer J, Nielsen S, Kim SY, Kim SZ, Kim SH, Kim SW (2008) Effects of alpha-lipoic acid on ischemia-reperfusion-induced renal dysfunction in rats

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Notably, MSCs demonstrated superior IL-6 suppression compared to nicorandil, suggesting enhanced anti-inflammatory efficacy that may reflect the complex paracrine signaling networks employed by MSCs, including secretion of TSG-6, PGE2, and other immunomodulatory factors 32,35