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MOA: Data curation, Methodology, Validation, Writing original draft, Writing review & editing

Intrinsically disordered N-terminus of calponin homology-associated smooth muscle protein (CHASM) interacts with the calponin homology domain to enable tropomyosin binding

13 If these proteins keep building up, they can disrupt neural communication and trigger widespread brain cell death

For the study, postdoctoral scientist Chi Kin Wong, induced systemic inflammation in mice by either injecting them with a bacterial cell wall component or a bacterial slur to induce sepsis, an extensive inflammation throughout the body that leads to organ damage