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Downstream molecules regulated by ncRNAs, P53, HSPB1, NRF2, and NOX2, key regulators of ferroptosis, are also involved in the regulation of other cell death types [65], suggesting that ferroptosis and other types of cell death are independent and related

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18 19 Issues with Nrf2 activation Whilst Nrf2 activation is undoubtedly beneficial in the vast majority of cases, there are some instances where it may prove harmful