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For the total population scenarios, men were projected to see a greater benefit from both SGLT2is and GLP-1 RAs than women, resulting in lower ICERs for men (the ICERs for SGLT2is were AU$20,361 per QALY for men and AU$28,377 per QALY for women, and those for GLP-1 RAs were AU$96,021 per QALY for men and AU$107,169 per QALY for women)

GLP-1 for Healthy Weight Loss GLP-1 (glucagon-like peptide-1 receptor agonists) medications are injectable treatments that mimic a natural hormone in the body to support weight loss

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Additionally, our metabolomics analysis of fullerenols exposure identified glutathione (GSH), a biomarker of oxidative stress, and experiments confirmed that fullerenols exposure leads to decreased glutathione levels in trophoblast cells