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For example, in clinical trials, nausea was reported in up to 44% of patients taking Wegovy at the maintenance dose

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In some specific experiments, the intestinal M-cells serve as a portal of entry of the hemagglutinin-botulinum toxin complex [49, 70]

GLP-1s do seem to quiet the food noise, and some of the survey data from the 102-week studies of GLP-1 use indicate a lot of this reduction in cravings and preoccupation with food remains reduced, though maybe at a slightly lower level than early on in treatment