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One of the most frequently investigated areas involves telomerase regulation , the enzyme associated with telomere maintenance

But the same disruption means the skin is more reactive to potential irritants in the formulation, including preservatives, fragrances, surfactants, and even some peptide stabilizers

Additionally, other DPP1 inhibitor candidates including BI 1291583 and HSK31858 have shown favorable clinical prospects in their respective development stages, with these research results further validating the enormous potential of DPP1 inhibition strategies as therapeutic approaches for respiratory diseases (Zhong et al., 2025