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Post hoc t -tests were performed to provide a measure toward proof of concept for various parameters at the end of dosing where the data distribution was assumed to be normal but this was not formally tested (Figs

Consistent with these results, ZnT8 was significantly upregulated and showed clear co-localization with INS + GCG + cells, with higher ZnT8 intensity in INS + GCG + cells than in INS + GCG cells (Supplementary information, Fig

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Another study revealed, using CARS2 heterozygous knockout mice, that CARS2 plays an anti-inflammatory role under various inflammatory conditions [79]