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The NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome is a central regulatory complex for pyroptosis in PD [40]

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The majority of BAMs originate during developmental stages, with the exception of the choroid plexus and dural macrophages, which are replenished by monocytes in adulthood [124, 125]

One week after the conditioning procedure, treatment was started and continued daily for two months, when mice were tested for behavioral performance, euthanized and brains collected for neuropathology