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Dietary modifications are often the first-line approach to managing stomach problems on Wegovy: Eat smaller, more frequent meals rather than large portions, as this reduces gastric distension and works with the delayed gastric emptying caused by semaglutide Avoid high-fat, greasy, or spicy foods , which can exacerbate nausea and slow digestion further Stay well hydrated , sipping water throughout the day, but avoid drinking large volumes with meals Limit alcohol and caffeine , both of which can irritate the gastric mucosa Avoid lying down immediately after eating

Even though risk adjustment is ostensibly designed to remove concerns about selection, it does not function perfectly, overpaying for some risks while underpaying for others

PMID 28514449

Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes