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In vitro effects of coital lubricants and synthetic and natural oils on sperm motility

Ceramide generation was a critical component of Fas receptor-induced eryptosis, whereas therapy with natural organosulfur compounds inhibited the apoptotic death of erythrocytes by antagonizing oxidative stress and the Gardos channel that led to suppression of ceramide-initiated Fas aggregation in lipid rafts of these erythrocytes

But, this cannot be the whole story as there are actually multiple EpRE elements in the promoters and not all of them are involved in regulating transcription (Dickinson et al., 2004)