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The messenger RNA expression levels of the (A) ACAT1, (B) SREBP-2, (C) HMGCR, (D) SQLE, (E) LXR, (F) CYP7A1, (G) LDLR, (H) PCSK9, (I) SR-B1, and (J) ABCA1 genes were analyzed by quantitative real-time polymerase chain reaction and normalized to that of the ACTB gene

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Additionally, purifying biosynthesized nanoparticles is challenging, as residual bio-organic compounds on Ag NPs surfaces may interfere with applications that require strict surface control and high chemical purity [276]