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Key takeaways TRIUMPH-4 is the first successful Phase 3 readout for retatrutide, reporting 28.7% mean body-weight reduction at 68 weeks on the 12 mg weekly dose (26.4% on 9 mg, 2.1% on placebo)

Site Rotation: Do not inject in the exact same spot every week

Protein Protein has long been associated with feeling fuller after meals, and GLP-1 helps explain why

Lipidomic analysis revealed significant molecular shifts in lipid subclasses based on the fatty acyl composition of lipid species, showing a trend toward higher unsaturation and longer carbon chain lengths, as well as metabolic regulation in specific lipid pathways