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Hunot S, Brugg B, Ricard D, Michel PP, Muriel MP, Ruberg M, et al

In conclusion, while there is no definitive evidence that glutathione causes skin cancer, the potential risks associated with its use, particularly the reduction of melanin levels, cannot be ignored

The high ROS environment lowers the activation threshold of mast cells, causing them to degranulate inappropriately and release a flood of inflammatory cytokines, including histamine, interleukins, and tumor necrosis factor-alpha (TNF-a)

Enzymatic activity assay A solution of the TPE-DCV and GSSG mixture (2.0 mL) was placed in a quartz cuvette (final concentration: [TPE-DCV] = 3 M, [GSSG] = 1 mM)