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Whatever path I've taken since, it all traces back to what was built there

The ELAD trial (Evaluating the Effects of the Novel GLP-1 Analogue Liraglutide in Alzheimers Disease) was a Phase 2b randomized, double-blind, placebo-controlled study in ~204 patients with mild AD

Firstly, some people believe that cerebral insulin resistance in patients with AD may not be insulin resistance in the true sense of the word but may instead arise from dysfunctional insulin transport across the BBB and that this transport defect may be caused by abnormal BBB function indirectly resulting from peripheral insulin resistance (Arnold et al., 2018)

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