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Pathological validation of the MDS criteria for the diagnosis of multiple system atrophy

Systemic human safety trials for injectable GHK-Cu are severely lacking, and the transition from topical cosmetic to systemic biologic introduces massive pharmacological variables

Increasing the reduces the mitochondrial [NAD + ]/[NADH] that may slow aging (Berry et al., 2023a,b) by both enhancing SLC25A12 and SLC25A13 activity to increase MAS activity and by creating thermodynamic back-pressure to slow ETC complex I-mediated proton pumping