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These data are used for regulatory approval

Similarly, high-dose liraglutide, when combined with caloric restriction and increased physical activity, has been shown to reduce both visceral fat and liver fat content, as measured by MRI and proton magnetic resonance spectroscopy ( 1 H-MRS), respectively, compared with placebo with lifestyle intervention alone in individuals with overweight or obesity at high ASCVD risk

Shikamura, M., Takayama, A., Takeuchi, M

However, the response of different cancer cells to this nutritional manipulation is highly variable, and the molecular determinants of this heterogeneity remain poorly understood