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The greatest difference was seen with semaglutide and tirzepatide

The $50 monthly copay is significantly less than what patients without any insurance coverage for obesity drugs typically pay

This weight reduction is substantial and noteworthy, especially considering that many conventional weight loss methods yield far less significant results

Additionally, it has been suggested that GIPR agonists and antagonists might target different CNS receptor populations, with evidence showing that acylated peptide GIPR agonists act on GABAergic neurons to further reduce food intake and body weight when combined with GLP-1R agonists in mice 39,40