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DOI: 10.1073/pnas.0308765101 Sntesis de acetilcolina y neuromodulacin Una vez que el ALCAR libera su grupo acetilo dentro de la neurona, este acetil-CoA puede ser utilizado por la colina acetiltransferasa (ChAT) para sintetizar acetilcolina a partir de colina: Acetil-CoA + Colina Acetilcolina + CoA (catalizado por ChAT) La acetilcolina es el neurotransmisor principal de: La corteza prefrontal (memoria de trabajo, atencin ejecutiva)