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At our institution, the standard-of-care protocol caps doses at 1 vial (1000 units) of glucarpidase because there is a lack of evidence to prove that higher doses of glucarpidase result in greater clinical benefit
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Berry-Kravis E, Hagerman R, Visootsak J, Budimirovic D, Kaufmann WE, Cherubini M, et al
The dosing approach typically follows an escalation protocol to minimize gastrointestinal side effects while achieving optimal receptor activation: The cagrilintide starting dose of 0.6 mg allows the body to adapt to amylin receptor activation gradually
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