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They can promote "natriuresis," which is a fancy term for the excretion of sodium through the urine

During the ISR, with global protein translation suppressed, untranslated mRNA transcripts and aggregation-prone RNA binding proteins such as Ras GTPase-activating protein-binding protein 1/2 (G3BP1/2) and T-cell-restricted intracellular antigen-1 related protein (TIAR) are packaged into non-membrane bound foci known as stress granules (SGs) [8]

Individuals with a known allergy to any of the components, pregnant or breastfeeding women, and those with liver disease or kidney disease should not take this medication

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