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This review covers the development of multi-agonist therapies, including GLP-1glucagon and GIPGLP-1glucagon receptor agonists, which represent a significant advancement in obesity treatment

Potency loss is minimal (less than 5%) during the first 28 days at correct refrigeration temperature, but accelerates rapidly if the vial experiences temperature excursions above 8C or light exposure

Mechanosensitive ion channels may also be involved in the early embryo-uterus crosstalk, as suggested by the high functional expression of the mechanosensitive PIEZO1 channels in epithelial cells of both mouse and human endometrium [40]