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After recovery from surgery, rats received a vehicle injection and 2 days later were randomly assigned to either of the diet groups (CHOW, fcHS, fcHF, or fcHFHS) and were maintained on their respective diets throughout the remainder of the experiment

This increase is caused by GLP-1 receptor activation in the sinoatrial node and autonomic nervous system, which shifts the balance toward sympathetic tone during dose titration

Two to three sessions per week targeting major muscle groups is sufficient

These include your weight loss goals, your response to the medication, any side effects you may experience, and underlying medical conditions present