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These symptoms warrant urgent evaluation to rule out cardiovascular complications

Phase 2 trial results, published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023), demonstrated that participants receiving the highest dose of retatrutide lost an average of approximately 24% of their body weight over 48 weeks a finding that attracted considerable attention from the medical and scientific communities

We also solicited comments on an alternative where a similar flat-point adjustment would be applied for ASM participants in rural areas