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In conclusion, neuropathy caused by diabetes is the primary cause of ejaculatory dysfunction, affecting nerve signal transmission and muscle coordination, potentially leading to retrograde ejaculation and other ejaculatory dysfunctions, further reducing male fertility

Protecting Lean Muscle Mass One of the most common concerns among GLP-1 patients is muscle loss

Seizure Threshold Considerations: Bupropion lowers the seizure threshold in a dose-dependent manner, which is why it is contraindicated in patients with seizure disorders

Also, the effect is minimal if taken irregularly or in very small doses (less than 500 mg per day)