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It does not raise cortisol or prolactin levels, which are hormones linked to stress and unwanted side effects

However, certain high-risk populations, including recent immigrants, individuals with HIV, and vulnerable urban populations, still experience a notable risk of TB (TB Incidence, 2024)

Its primary symptoms include headache, vomiting [1, 2], and gait abnormalities, In severe cases, HACE can also lead to cognitive impairments, such as difficulty concentrating and memory loss [3]

The patients were followed up for 6 months and demonstrated a significant decrease in pain assessed by both measures at all assessments and reported no adverse events [12]