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Briefly, mice were placed in a gray square box (50 50 50 cm) with visual cues on the walls

While the clinical significance remains under investigation, practitioners should monitor cardiovascular parameters in patients with pre-existing risk factors

This cyclic pathway, catalyzed by NO synthase (NOS), facilitates the continuous conversion of L-arginine to L-citrulline and NO ( Figure 2a ) ( Figure 2e ) ( Figure 2 3.2 Biological basis of multi-organ protective effects The multi-organ protective effects of L-citrulline are principally attributed to its capacity for systemic modulation of NO signaling

Proc Natl Acad Sci USA (2001) 98(5):28559