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Cagrilintide has been studied in combination with semaglutide as a fixed-dose therapy, with promising results: the combination amplified weight loss compared to semaglutide alone, while preserving lean mass better than monotherapy

In some cases, injections also improve treatment adherence compared to oral vitamin B12 supplements

The team focused on results from 308 participants who had lost at least 10% of their body weight by the end of the initial 36-week period before switching to the placebo, finding that one year after stopping tirzepatide, 82% of these participants had regained 25% or more of their initial weight reduction

AOD 9604 is not an FDA-approved weight loss drug and any use should be discussed with a licensed medical provider