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Selective serotonin reuptake inhibitors (SSRIs) The most prescribed type of antidepressant They work by blocking some reuptake of serotonin, helping elevate mood Serotonin and norepinephrine reuptake inhibitors (SNRIs) Similar to SSRIs They work by blocking reuptake of both serotonin and norepinephrine to help elevate mood Tricyclic antidepressants (TCAs) An older class of antidepressant They are stronger but have more side effects and are usually only prescribed when other, newer types of antidepressants dont work Monoamine oxidase inhibitors (MAOIs) One of the first class of antidepressants on the market Usually only prescribed when all other categories of antidepressants have failed to work because they have serious side effects and interactions with foods and other medicines Other types of antidepressants A norepinephrine and dopamine reuptake inhibitor (NDRI) is another type of antidepressant that works differently than SSRIs or SNRI Sedating antidepressants may also be used to help treat insomnia What Are the Side Effects of Melatonin

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