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These findings suggest that urinary ferritin not only reflects iron overload in the renal tubule, but also may be used as a sensitive indicator of early renal tubular injury in DKD

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Prevention of nitrosative stress by a nutritional supplement (LaVita)A randomized placebo controlled double blind clinical trial with healthy volunteers

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These factors collectively drive the progressive damage of biliary epithelial cells by autoantibodies, leading to cholestasis, fibrosis, and potential progression to cirrhosis or liver failure (217)

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