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126 While the roles of traditional macrophage subsets like KCs in liver regeneration have been well-documented, recent research has begun to shed light on the diverse and dynamic nature of the macrophage pool, particularly how it evolves from birth through repeated injury and regeneration cycles

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However, these methods may not be sufficient for individuals with significantly depleted levels

Mitochondrial dysfunction and ROS Reactive oxygen species (ROS) are highly reactive molecules with a free oxygen that easily react with other molecules