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Long-term human safety data are not yet established

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There was a mean 9.8% increase in the relative abundance of Akkermansia muciniphila , 58.5% increase in Faecalibacterium prausnitzii , 18.2% decrease in Coprococcus eutectus , and 26.3% decrease in Roseburia faecis at week 14 compared to baseline (Figure S1)

The study is strengthened by its large-scale AI-based analysis of social media discussions to uncover public perceptions and experiences with drugs, offering insights beyond traditional clinical research