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PubMed Loose, sagging skin (cheeks, jawline, neck) Lower elastin and collagen with weight-lossassociated skin redundancy contribute to jowling and neck laxity

[3][4] Phase 2 clinical trials demonstrated a safety profile generally consistent with the GLP-1/GIP/glucagon agonist class, with no unexpected safety signals during the 48-week study period

Yes, many patients use nausea relief medications alongside GLP-1 therapies such as Semaglutide or Tirzepatide to ease digestive discomfort that can occur when starting these treatments

Rescue therapy was needed by 8%, 25%, and 67%, respectively. Five milligrams preserved most, but not all, of the benefit of continuing the effective dose